Droplets, Membranes and Interfaces
Jean-Christophe Baret is an independent Max-Planck Research Group Leader at MPI-DS since 2010. His expertise deals with complex fluids (droplets, emulsions, surfactants) and microfluidics (electrocapillarity, droplet-based microfluidics). The context of his research is high-throughput screening of micro-organisms, genes or drugs with a focus on directed evolution of enzymes and quantitative analysis of single cells in populations. He has recently been granted an ERC starting grant for a project combining microfluidics, soft matter and biotechnology.
Skhiri Y, Gruner P, Semin B, Brosseau Q, Pekin D, Mazutis L, Goust V, Kleinschmidt F, El Harrak A, Hutchison JB, Mayot E, Bartolo JF, Griffiths AD, Taly V, Baret JC: Dynamics of molecular transport by surfactants in emulsions, Soft Matter 8 (2012) 10618-10627
Miller OJ, El Harrak A, Mangeat T, Baret JC, Frenz L, El Debs B, Mayot E, Samuels ML, Rooney EK, Dieu P, Galvan M, Link DR, Griffiths AD: High-resolution dose-response screening using droplet-based microfluidics, Proc. Natl. Acad. Sci. U S A 10 (2012) 378-383
Agresti JJ, Antipov E, Abate AR, Ahn K, Rowat AC, Baret JC, Marquez M, Klibanov AM, Griffiths AD, Weitz DA: Ultrahigh-throughput screening in drop-based microfluidics for directed evolution (2010), Proc. Natl. Acad. Sci. U S A 107 (2010) 4004
Baret JC, Miller OJ, Taly V, Ryckelynck M, El-Harrak A, Frenz L, Rick C, Samuels ML, Hutchison JB, Agresti JJ, Link DR, Weitz DA, Griffiths AD: Fluorescence-activated droplet sorting (FADS): efficient microfluidic cell sorting based on enzymatic activity, Lab Chip 9 (2009) 1850