Independent Research Group of
Engineering of genetic systems for bottom-up synthetic biology
Max Planck Institute for Biochemistry, Martinsried
The group of Hannes Mutschler at the MPIB interested in the bottom-up reconstitution of minimal genetic systems capable of recursive replication and Darwinian Evolution. In addition, the group is exploring different prebiotic environments for their ability to assist the emergence and proliferation of primitive RNA-enzymes and protocells. To achieve these goals, the Mutschler group employs a variety of methods from protein and nucleic acid biochemistry, genome assembly, directed evolution, and deep sequencing.