Publications of the Spatz Group

Journal Article (39)

2021
Journal Article
Jahnke, K.; Ritzmann, N.; Fichtler, J.; Nitschke, A.; Dreher, Y.; Abele, T.; Hofhaus, G.; Platzman, I.; Schröder, R. R.; Müller, D. J. et al.; Spatz, J. P.; Göpfrich, K.: Proton gradients from light-harvesting E. coli control DNA assemblies for synthetic cells. Nature Communications 12, 3967 (2021)
Journal Article
Staufer, O.; Antona, S.; Zhang, D.; Csatári, J.; Schröter, M.; Janiesch, J.-W.; Fabritz, S.; Berger, I.; Platzman, I.; Spatz, J. P.: Microfluidic production and characterization of biofunctionalized giant unilamellar vesicles for targeted intracellular cargo delivery. Biomaterials 264, 120203 (2021)
Journal Article
Staufer, O.; De Lora, J. A.; Bailoni, E.; Bazrafshan, A.; Benk, A. S.; Jahnke, K.; Manzer, Z. A.; Otrin, L.; Díez Pérez, T.; Sharon, J. et al.; Steinkühler, J.; Adamala, K. P.; Jacobson, B.; Dogterom, M.; Göpfrich, K.; Stefanovic, D.; Atlas, S. R.; Grunze, M.; Lakin, M. R.; Shreve, A. P.; Spatz, J. P.; López, G. P.: Building a community to engineer synthetic cells and organelles from the bottom-up. eLife 10, e73556 (2021)
Journal Article
Staufer, O.; Dietrich, F.; Rimal, R.; Schröter, M.; Fabritz, S.; Boehm, H.; Singh, S.; Möller, M.; Platzman, I.; Spatz, J. P.: Bottom-up assembly of biomedical relevant fully synthetic extracellular vesicles. Science Advances 7, eabg6666 (2021)
2020
Journal Article
Antona, S.; Abele, T.; Jahnke, K.; Dreher, Y.; Göpfrich, K.; Platzman, I.; Spatz, J. P.: Droplet‐Based Combinatorial Assay for Cell Cytotoxicity and Cytokine Release Evaluation. Advanced Functional Materials 30, 2003479 (2020)
Journal Article
Antona, S.; Platzman, I.; Spatz, J. P.: Droplet-Based Cytotoxicity Assay: Implementation of Time-Efficient Screening of Antitumor Activity of Natural Killer Cells. ACS Omega 5, pp. 24674 - 24683 (2020)
Journal Article
Dreher, Y.; Jahnke, K.; Bobkova, E.; Spatz, J. P.; Göpfrich, K.: Division and regrowth of phase‐separated giant unilamellar vesicles. Angewandte Chemie International Edition (2020)
Journal Article
Frey, C.; Pfeil, J.; Neckernuss, T.; Geiger, D.; Weishaupt, K.; Platzman, I.; Marti, O.; Spatz, J. P.: Label‐free monitoring and manipulation of microfluidic water‐in‐oil droplets. View 1, 20200101 (2020)
Journal Article
Frey, C.; Göpfrich, K.; Pashapour, S.; Platzman, I.; Spatz, J. P.: Electrocoalescence of Water-in-Oil Droplets with a Continuous Aqueous Phase: Implementation of Controlled Content Release. ACS Omega 5 (13), pp. 7529 - 7536 (2020)
Journal Article
Göpfrich, K.; Urban, M. J.; Frey, C.; Platzman, I.; Spatz, J. P.; Liu, N.: Dynamic Actuation of DNA-Assembled Plasmonic Nanostructures in Microfluidic Cell-Sized Compartments. Nano Letters 20 (3), pp. 1571 - 1577 (2020)
Journal Article
Haller, B.; Jahnke, K.; Weiss, M.; Göpfrich, K.; Platzman, I.; Spatz, J. P.: Autonomous Directional Motion of Actin‐Containing Cell‐Sized Droplets. Advanced Intelligent Systems, 2000190 (2020)
Journal Article
Jahnke, K.; Weiss, M.; Weber, C.; Platzman, I.; Göpfrich, K.; Spatz, J. P.: Engineering Light‐Responsive Contractile Actomyosin Networks with DNA Nanotechnology. Advanced Biosystems 4, p. 2000102 (2020)
Journal Article
Luo, R.; Göpfrich, K.; Platzman, I.; Spatz, J. P.: DNA‐Based Assembly of Multi‐Compartment Polymersome Networks. Advanced Functional Materials 30, 2003480 (2020)
Journal Article
Luo, R.; Pashapour, S.; Staufer, O.; Platzman, I.; Spatz, J. P.: Polymer‐Based Porous Microcapsules as Bacterial Traps. Advanced Functional Materials, 1908855 (2020)
Journal Article
Lussier, F.; Staufer, O.; Platzman, I.; Spatz, J. P.: Can Bottom-Up Synthetic Biology Generate Advanced Drug-Delivery Systems? Trends in Biotechnology (2020)
Journal Article
Staufer, O.; Schröter, M.; Platzman, I.; Spatz, J. P.: Bottom‐Up Assembly of Functional Intracellular Synthetic Organelles by Droplet‐Based Microfluidics. Small, 1906424 (2020)
Journal Article
Young, J. L.; Hua, X.; Somsel, H.; Reichart, F.; Kessler, H.; Spatz, J. P.: Integrin Subtypes and Nanoscale Ligand Presentation Influence Drug Sensitivity in Cancer Cells. Nano Letters 20 (2), pp. 1183 - 1191 (2020)
2019
Journal Article
Göpfrich, K.; Haller, B.; Staufer, O.; Dreher, Y.; Mersdorf, U.; Platzman, I.; Spatz, J. P.: One-Pot Assembly of Complex Giant Unilamellar Vesicle-Based Synthetic Cells. ACS Synthetic Biology 8 (5), pp. 937 - 947 (2019)
Journal Article
Jahnke, K.; Weiss, M.; Frey, C.; Antona, S.; Janiesch, J.-W.; Platzman, I.; Göpfrich, K.; Spatz, J. P.: Programmable Functionalization of Surfactant‐Stabilized Microfluidic Droplets via DNA‐Tags. Advanced Functional Materials 29 (23), 1808647 (2019)
2018
Journal Article
Göpfrich, K.; Platzman, I.; Spatz, J. P.: Mastering Complexity: Towards Bottom-up Construction of Multifunctional Eukaryotic Synthetic Cells. Trends in Biotechnology 36 (9), pp. 938 - 951 (2018)
Journal Article
Haller, B.; Göpfrich, K.; Schröter, M.; Janiesch, J.-W.; Platzman, I.; Spatz, J. P.: Charge controlled microfluidic formation of lipid-based single- and multicompartment systems. Lab on a Chip 18, pp. 2665 - 2674 (2018)
Journal Article
Juniper, M. P.N.; Weiss, M.; Platzmann, I.; Spatz, J. P.; Surrey, T.: Spherical network contraction forms microtubule asters in confinement. Soft Matter 14, pp. 901 - 909 (2018)
Journal Article
Schwille, P.; Spatz, J.; Landfester, K.; Bodenschatz, E.; Herminghaus, S.; Sourjik, V.; Erb, T.; Bastiaens, P.; Lipowsky, R.; Hyman, A. et al.; Dabrock, P.; Baret, J. P.; Vidaković-Koch, T.; Bieling, P.; Dimova, R.; Mutschler, H.; Robinson, T.; Tang, D.; Wegner, S.; Sundmacher, K.: MaxSynBio - Avenues towards creating cells from the bottom up. Angewandte Chemie International Edition 57 (41), pp. 13382 - 13392 (2018)
Journal Article
Schwille, P.; Spatz, J. P.; Landfester, K.; Bodenschatz, E.; Herminghaus, S.; Sourjik, V.; Erb , T.; Bastiaens, P.; Lipowsky, R.; Hyman, A. A. et al.; Dabrock, P.; Baret, J.-C.; Vidaković-Koch, T.; Bieling, P.; Dimova, R.; Mutschler , H.; Robinson, T.; Tang, T.-Y. D.; Wegner, S.; Sundmacher, K.: MaxSynBio: Wege zur Synthese einer Zelle aus nicht lebenden Komponenten. Angewandte Chemie 130 (41), pp. 13566 - 13577 (2018)
Journal Article
Vishwakarma, M.; Di Russo, J.; Probst, D.; Schwarz, U. S.; Das, T.; Spatz, J. P.: Mechanical interactions among followers determine the emergence of leaders in migrating epithelial cell collectives. Nature Communications 9, 3469 (2018)
Journal Article
Weiss, M.; Frohnmayer, J. P.; Benk, L. T.; Haller, B.; Janiesch, J.-W.; Heitkamp, T.; Börsch, M.; Lira, R. B.; Dimova, R.; Lipowsky, R. et al.; Bodenschatz, E.; Baret, J.-C.; Vidaković-Koch, T.; Sundmacher, K.; Platzman, I.; Spatz, J. P.: Sequential bottom-up assembly of mechanically stabilized synthetic cells by microfluidics. Nature Materials 17, pp. 89 - 96 (2018)
2017
Journal Article
Pallarola, D.; Platzmann, I.; Bochen, A.; Cavalcanti-Adam, E. A.; Axmann, M.; Kessler, H.; Geiger, B.; Spatz, J. P.: Focal adhesion stabilization by enhanced integrin-cRGD binding affinity. BioNanoMaterials 18 (1-2), 20160014 (2017)
Journal Article
Zamir, E.; Frey, C.; Weiss, M.; Antona, S.; Frohmayer, J. P.; Janiesch, J.-W.; Platzman, I.; Spatz, J. P.: Reconceptualizing fluorescence correlation spectroscopy for monitoring and analyzing periodically passing objects. Analytical Chemistry 89 (21), pp. 11672 - 11678 (2017)
2016
Journal Article
Guasch, J.; Diemer, J.; Riahinezhad, H.; Neubauer, S.; Kessler, H.; Spatz, J. P.: Synthesis of Binary Nanopatterns on Hydrogels for Initiating Cellular Responses. Chemistry of Materials 28 (6), pp. 1806 - 1815 (2016)
Journal Article
Schaufler, V.; Czichos-Medda, H.; Hirschfeld-Warnecken, V.; Neubauer, S.; Rechenmacher, F.; Medda, R.; Kessler, H.; Geiger, B.; Spatz, J. P.; Cavalcanti-Adam, E. A.: Selective binding and lateral clustering ofα5β1 andαvβ3 integrins: Unraveling the spatial requirements for cell spreading and focal adhesion assembly. Cell Adhesion & Migration 10, pp. 505 - 515 (2016)
Journal Article
Schaufler, V.; Czichos-Medda, H.; Hirschfeld-Warnecken, V.; Neubauer, S.; Rechenmacher, F.; Medda, R.; Kessler, H.; Geiger, B.; Spatz, J. P.; Cavalcanti-Adam, E.A.: Selective binding and lateral clustering of α5β1 and αvβ3 integrins: Unraveling the spatial requirements for cell spreading and focal adhesion assembly. Cell Adhesion & Migration 10 (5), pp. 505 - 515 (2016)
Journal Article
Wegner, S.; Schenk, F. C.; Spatz, J. P.: Cobalt(III)-Mediated Permanent and Stable Immobilization of Histidine-Tagged Proteins on NTA-Functionalized Surfaces. Chemistry – A European Journal 22 (9), pp. 3156 - 3162 (2016)
Journal Article
Wegner, S.; Schenk, F. C.; Witzel, S.; Bialas, F.; Spatz, J. P.: Cobalt Cross-Linked Redox-Responsive PEG Hydrogels: From Viscoelastic Liquids to Elastic Solids. Macromolecules 49 (11), pp. 4229 - 4235 (2016)
Journal Article
Young, J. L.; Holle, A. W.; Spatz, J. P.: Nanoscale and mechanical properties of the physiological cell-ECM microenvironment. Experimental Cell Research 343 (1), pp. 3 - 6 (2016)
2015
Journal Article
Das, T.; Safferling, K.; Rausch, S.; Grabe, N.; Böhm, H.; Spatz, J. P.: A molecular mechanotransduction pathway regulates collective migration of epithelial cells. Nature Cell Biology 17, pp. 276 - 287 (2015)
Journal Article
Frohnmayer, J.; Brüggemann, D.; Eberhard, C.; Neubauer, S.; Mollenhauer, C.; Böhm, H.; Kessler, H.; Geiger, B.; Spatz, J. P.: Minimal synthetic cells to study integrin-mediated adhesion. Angewandte Chemie International Edition 54 (42), pp. 12472 - 12478 (2015)
Journal Article
Guasch, J.; Conings, B.; Neubauer, S.; Rechenmacher, F.; Ende, K.; Rolli, C. G.; Kappel, C.; Schaufler, V.; Micoulet, A.; Kessler, H. et al.; Boyen, H.-G.; Cavalcanti-Adam, E. A.; Spatz, J. P.: Segregation Versus Colocalization: Orthogonally Functionalized Binary Micropatterned Substrates Regulate the Molecular Distribution in Focal Adhesions. Advanced Materials 27 (25), pp. 3737 - 3747 (2015)
Journal Article
Janiesch, J.-W.; Weiss, M.; Kannenberg, G.; Hannabuss, J.; Surrey, T.; Platzman, I.; Spatz, J. P.: Key factors for stable retention of fluorophores and labeled bio-molecules in droplet-based microfluidics. Analytical Chemistry 87 (4), pp. 2063 - 2067 (2015)
Journal Article
Raoufi, M.; Das, T.; Schoen, I.; Vogel, V.; Brüggemann, D.; Spatz, J. P.: Nanopore Diameters Tune Strain in Extruded Fibronectin Fibers. Nano Letters 15 (10), pp. 6357 - 6364 (2015)

Book Chapter (2)

2019
Book Chapter
Frohnmayer, J. P.; Weiss, M.; Benk, L. T.; Janiesch, J.-W.; Haller, B.; Lira, R. B. d.; Dimova, R.; Platzman, I.; Spatz, J. P.: Droplet-stabilized giant lipid vesicles as compartments for synthetic biology. In: The Giant Vesicle Book, pp. 601 - 617. CRC Press (2019)
2015
Book Chapter
Platzman, I.; Kannenberg, G.; Janiesch, J.-W.; Matić, J.; Spatz, J. P.: PEG-Based Antigen-Presenting Cell Surrogates for Immunological Applications, Soft Matter Nanotechnology: From Structure to Function. In: Soft Matter Nanotechnology: From Structure to Function, pp. 187 - 216 (Ed. Chen, X.). Wiley-VCH, Weinheim (2015)

Working Paper (1)

2019
Working Paper
Dreher, Y.; Spatz, J. P.; Göpfrich, K.: Protein-free division of giant unilamellar vesicles controlled by enzymatic activity. bioRxiv (2019), 24 pp.
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